Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma

A Singh, S Mishra, S Sharma, S Ojha… - … Cancer Drug Targets, 2023 - ingentaconnect.com
Sorafenib-loaded lactobionic acid conjugated G(4)PAMAM-FITC dendrimers were
investigated by Iacobazzi and co-workers for the targeting of human liver cancer cells. …

Nanotechnology based approach for hepatocellular carcinoma targeting

A Alhalmi, S Beg, K Kohli, M Waris… - … Drug Targets, 2021 - ingentaconnect.com
… the liver tumor cells, therefore, increase selective targeting of … and lactobionic acid (MSN-CS-LA
nanocarriers) to target … have shown that sorafenib loaded with dendrimer exhibits superi…

Targeted delivery of miR-218 via decorated hyperbranched polyamidoamine for liver cancer regression

AM Elfiky, RH Mohamed, FEZ Abd EL-Hakam… - International Journal of …, 2021 - Elsevier
… high loading efficiency of DNA and enhances the cellular … to the widely used PAMAM
dendrimer (G4) which needs multi-… LA moieties against human liver carcinoma cell line (HepG2). …

Expatiating the pivotal role of Dendrimers as emerging nanocarrier for management of Liver Disorders

N Sharma, I Zahoor, S Singh, T Behl… - Journal of Integrated …, 2023 - pubs.thesciencein.org
… Patent literature status related to application of dendrimers in liver disorders … Targeting
human liver cancer cells with lactobionic acid-G (4)-PAMAM-FITC sorafenib loaded dendrimers. Int…

Dendrimer as imaging contrast agents

RM Iacobazzi, N Denora - Dendrimer-Based Nanotherapeutics, 2021 - Elsevier
dendrimer encapsulating the anticancer drug sorafenib and … targeting specificity of Ac-La-G(4)-PAMAM-FITC
dendrimerTargeting human liver cancer cells with lactobionic acid-G(4)-…

Preparation and evaluation of folate-decorated human serum albumin nanoparticles for the targeted delivery of sorafenib to enhance antihepatocarcinoma efficacy

W Gao, X Jia, J Wu, Y Song, J Yin, M Zhang… - Journal of Drug Delivery …, 2019 - Elsevier
… -human serum albumin-sorafenib nanoparticles (FA-HSA-SRF-NPs) to improve the active-targeting
to liver tumor cellssorafenib-loaded human serum albumin nanoparticles with active-…

In vitro/vivo antitumor study of modified-chitosan/carboxymethyl chitosan “boosted” charge-reversal nanoformulation

L Li, P Zhang, C Li, Y Guo, K Sun - Carbohydrate Polymers, 2021 - Elsevier
… The ideal anticancer nanoformulations for tumor-targeted … exerted to kill the tumor cells and
inhibit the tumor growth. However, … However, cationic PAMAM dendrimers could be rapidly …

[HTML][HTML] Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways

H Kheraldine, I Gupta, H Alhussain, A Jabeen… - Computational and …, 2021 - Elsevier
… GAPDH was used as a control for the loaded amount of the … dendrimers on HER2-positive
human breast cancer cell lines (… line models, we investigated the downstream target of HER1 …

The pharmaceutical technology approach on imaging innovations from Italian research

G Ailuno, RM Iacobazzi, A Lopalco, S Baldassari… - Pharmaceutics, 2021 - mdpi.com
… drug sorafenib, which is able to targethuman liver cancer cells, characterized by undetectable
level of receptor, confirmed the targeting specificity of Ac-La-G(4)-PAMAM-FITC dendrimer

Biomaterial-mediated exogenous facile coating of natural killer cells for enhancing anticancer efficacy toward hepatocellular carcinoma

AK Jangid, S Kim, HJ Kim, K Kim - Bioconjugate Chemistry, 2023 - ACS Publications
… Clicking on the donut icon will load a page at altmetric.com … , and (3) lactobionic acid (LBA)
for cancer recognition. The … between engineered NK cells and target liver cancer cells, and …